In defence of the million mythical genders, some Leftists point out that historically, there were several cultures which believed in extra genders. Some Native American tribes, for example, had a third gender: "Two spirit". The simple response to this is that the men still produced the sperm, and the women still carried the babies.
Biologically speaking, there are only two genders. Human beings are designed to reproduce in a specific way. Even in our modern era, in which IVF is an alternative, human beings cannot reproduce until sperm (from the male) meets egg (from the female). Naturally, we cannot reproduce alone, we cannot reproduce with members of the same gender, and we cannot survive more than one generation without the natural union of male and female.
The facts described above are cold, hard science. Science does not care about your ideology, nor does it care about your feelings. You can identify as whatever you want, you can hold others to ransom until they acknowledge your chosen identity, you cannot change the fact that you are what you are. If you are male, you are male. If you are female, you are female. You cannot be "two spirit", nor can you be "a woman trapped in a man's body". If you're offended by that, the problem is with you, not the reality you're having trouble accurately perceiving.
But why do some people have such trouble perceiving this reality? Why are they so offended when they only hear the truth? Biblically speaking, it's because we all are. Ever since the fall of man, we have lived in, and loved living in the darkness. Each of us has gone our own way, and if God gets in the way of that, we nail Him to a cross.
And He lets us.
The great thing about God is that while He hates sin so much that it must be punished, He loves us so much that He'd rather not punish us. Therefore, He punished Jesus in our stead. Unlike us, Jesus never knew sin. Therefore, He deserved no punishment. Yet, He received it on our behalf so that we, who love darkness, may cross over into the light. Our relationship with God will be restored, and we will live with Him forever. But only if we confess Him as Lord, and believe He rose from the dead.