One unique thing about life is it has free will. Within physical constraints, living beings can make any number of choices about their current situation. Imagine if this was not the case. Would science be worth attempting? If the thing being tested could choose the outcome of the experiment, we couldn't even know what was safe to eat. The very chemicals our bodies are made of could choose to rebel against us.
But as it stands, chemicals have no free will. Perform the same experiment over and over again, you'll get roughly the same result. Anomalies are due to variables, not the choice of the things being experimented on. Because of this, we cannot hold chemicals accountable for crime. We can't blame water for drowning a man, for example.
But we can blame another man for holding the victim's head under water. This is because the human being is more than mere chemicals. Unlike even the chemicals we are made of, we have the ability to make conscious choices. Therefore, it is possible to hold us accountable for them. Every time we do so, we prove inherent knowledge that the human spirit exists, and Naturalism, along with the philosophies that spring from it, are wrong.
Unfortunately for us, we are ultimately accountable to God, against whom we have made numerous wrong choices over the course of our lives. By nature, we rebel against Him on a regular basis, the punishment for which is death. But this is not His desire. Rather, He instead chose to punish Jesus on our behalf. Jesus died on the cross, taking the full wrath of God, allowing all who will confess Him to receive forgiveness and inherit eternal life. Since you are not just a collection of chemicals, you have the ability to do so.