The irony of the chief priests and Pharisees seeking to lay hands on Jesus because they perceived His parables were about them is that the parable in question says this is exactly what they will do. Jesus had told a parable about a man who leased out a field, then sent out his servants to collect the fruits, but the people to whom the field was leased killed the servants, so the owner sent another set, who were also killed, and finally his son, whom they killed, so naturally the owner killed them in retaliation.
So, effectively, the chief priests and Pharisees, perceiving that Jesus was speaking about them, sought to do exactly the thing He said they were doing. In other words, this is the most self-condemning action in history.
Eventually, of course, the Jews did succeed in killing Jesus. But unlike the son in the parable, the Son of God did not stay dead. He rose again. In Acts 2:36-39, we read "“Therefore let all the house of Israel know assuredly that God has made this Jesus, whom you crucified, both Lord and Christ.” Now when they heard this, they were cut to the heart, and said to Peter and the rest of the apostles, “Men and brethren, what shall we do?” Then Peter said to them, “Repent, and let every one of you be baptized in the name of Jesus Christ for the remission of sins; and you shall receive the gift of the Holy Spirit. For the promise is to you and to your children, and to all who are afar off, as many as the Lord our God will call.”"
That the Jews are God's chosen people is a deep statement. Romans 11 compares it to an olive tree: God is the root, the Jews are the natural branches, and the gentiles are the branches of wild olive trees who are grafted in. The Jews can be easily broken off, and when they laid hands on Jesus and crucified Him, they did exactly that. To this day, many Jews continue to reject Him, and thus are also "broken off." But the good news of the Gospel is that they can be grafted back in exactly the manner described in Acts 2:36-39: Repent, and let every one of you be baptized in the name of Jesus Christ for the remission of sins. Such mercy from God, that though you can be absolutely sure He will repay those who refuse to repent, you can be just as sure that those who do repent will be forgiven.